![]() ![]() You can also try getting more celery into your diet to help reduce the frequency or severity of gout attacks.Ĭelery stalks and celery juice are a healthy food choice, but they don’t contain as many of the beneficial compounds as the seeds and oil. Recommended dosage is three capsules per day. Swanson’s Celery Seed (500 mg): Contains 500 mg per capsule.Recommended dosage is two capsules per day. Solaray’s Celery Seed (505 mg): Contains 505 mg per capsule.Recommended dosage is one capsule twice per day. Natural Factors’ Celery Seed Standardized Extract (85% 3nB): Contains 75 mg celery seed/63.75 mg 3nB extract per serving.Here are a few recommendations for celery seed supplements that might be beneficial for gout, although you should speak with your doctor first: With many different standardizations, the dosages may differ between supplements. These extracts have been standardized to contain certain percentages of beneficial compounds, such as luteolin or 3nB. Research studies on celery seed, like many botanical medicine studies, primarily use hydroalcoholic extracts. inhibition of xanthine oxidase: 100 micrograms per milliliter (μg/mL).reduction of uric acid levels: 1,000 milligrams per kilogram (mg/kg) for two weeks.reduction of serum uric acid and antioxidant activity: 5 grams per kilogram (g/kg).Current research on celery seed has shown benefits at the following dosages: ![]() However, various research studies may give us a starting place for beneficial dosages in humans. Most celery seed studies are either animal studies or in vitro studies, so there’s a lack of research exploring celery seed in human dosages. These properties may be especially beneficial in reducing inflammation in conditions such as gout. There are a handful of other compounds in celery seed that may exhibit other antioxidant and anti-inflammatory properties. These benefits may also be found in the beta-selinene in celery seed, but this study didn’t test celery specifically. The results showed that beta-selinene demonstrated a wide variety of antioxidant and anti-inflammatory properties. One study on Varbenaceae, a medicinal herb, examined the antioxidant properties of beta-selinene. These results indicate that celery seed may help reduce gout-related inflammation. In a recent study, researchers discovered that exposing certain cells to 3nB reduced both oxidative stress and pro-inflammatory pathways. Reducing uric acid levels with luteolin might reduce the frequency of gout flare-ups.ģ-n-butylphthalide (3nB) is another compound from celery that may have benefits against gout inflammation. Xanthine oxidase is an enzyme in the purine pathway, which produces the by-product of uric acid. In one in vitro study, it was revealed that luteolin is one of the flavonoids that can inhibit xanthine oxidase. In addition, luteolin is a flavonoid that may directly reduce uric acid production. However, more research in humans is needed. ![]() This study suggests that luteolin might provide some protection from uric acid-induced inflammation in gout. The researchers found that luteolin from celery seeds reduced the production of nitric oxide from uric acid. Nitric oxide is an important compound in the body, but it can produce oxidative stress and inflammation in large amounts. In one animal study, researchers investigated the impact of luteolin on nitric oxide produced from uric acid. ![]() These compounds have been researched for their role in inflammation and uric acid production, which is a driving force behind the severity of gout attacks. The most notable compounds in celery seed include: Celery ( Apium graveolens) contains many beneficial plant compounds, which are found primarily in the seeds of the plant. ![]()
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